Figure 3. Transcription factors differentially regulate the activity of the same enhancers in different appendages. (left) FAIRE, RNA, and Ubx ChIP (Slattery et al, 2011) signal at the Distalless locus in imaginal discs. Enhancer locations are designated by green boxes. (right) Confocal images showing reporter activity of the DLL04 enhancer in wing and haltere imaginal discs. Note the different patterns of DLL04 activity despite identical open chromatin profiles.