Overview
We focus on the central question of how information encoded in the genome is differentially accessed to generate and maintain a diversity of cell types during development. There are two main projects in the lab:
Project 1: The role of histones as carriers of epigenetic information.
The objective of this project is to determine the contribution made by histone post-translational modifications (PTMs) in establishing and maintaining epigenetic identity (read more).
Project 2: Dynamic control of DNA regulatory elements.
The objective of this project is to determine how transcription factors dynamically access enhancers that are packaged in chromatin during development. (read more).
